Table 3

Effect of single-dose DOX or PLED (2 mg/kg) plus single-fraction RT against KB xenograft tumors in nude mice. Median times to reach 3Vo and statistical analyses

Median time to 3Vo (days)
Group4.5 Gy9 Gy
No drug12.722.6
DOX plus RT15.230.5
PLED plus RT24.635.4
Group4.5 Gy9 Gy
RT vs. DOX plus RT<0.02>0.1
RT vs. PLED plus RT<0.0010.1 > P > 0.05
DOX plus RT vs. PLED plus RT<0.05>0.1