Table 1

EGFR gene expression in various human tumors as determined by IHC and RT-PCR

Tumors were xenografted to NCR-nu mice and, after growth to an average diameter of 1 ± 0.2 cm, excised for EGFR gene expression analysis. Other experimental details are described in the text. Averages of two experiments are shown.

TumorTumor typeRelative EGFR Gene Expression
IHCaRT-PCRb
A431Vulvar1010
SK-LC-16NSCLc22
A549NSCLc12
PC-3Prostate12
TSU-PR1Prostate±1
LX-1Lung0<1
  • a The intensity of the specific staining for each tumor was compared with that seen with A431.

  • b The amount of PCR product shown in Fig. 1<$REFLINK> was compared with that obtained with A431.

  • c NSCL, non-small cell lung cancer.