Table 1

Relationship between p53 mutation positivity and clinical features with advanced NSCLC

p53 mutationPa
PositiveNegative
Sex
Male25260.550
Female415
Age (yr)
<7020190.088
≥70922
Histological type
Squamous cell carcinoma9100.538
Adenocarcinoma plus large cell carcinoma2031
Clinical stage
III9210.141
IV2020
Performance status
0–12028
2–4913>0.999
Loss of body weight
<5%22350.361
>5%76
Serum LDH
Normal7180.129
Abnormal2223
Smoking (pack-years)
0–4917280.454
<501213
  • a 2×2 Fisher’s exact test was used.