Table 2

Univariate analysis of various parameters as prognostic factors in patients with advanced NSCLC

Prognostic factorNo. of patientsMedian survival time (weeks)Pa
p53 mutation
Negative41390.0003
Positive2917
Sex
Male51280.190
Female1935
Age (yr)
<7039370.519
≥703126
Histologic type
Squamous cell carcinoma19290.629
Adenocarcinoma plus large cell carcinoma5128
Clinical stage
III3036
IV40220.024
Performance status
0–14845<0.0001
2–42211
Loss of body weight
<5%57340.054
≥5%1328
Serum LDH
Normal25500.015
Abnormal4517
  • a Log-rank test was used to analyze survival differences.