Table 1

Frequencies of polymorphism at codon 389 (AAC to AAT) in patients with ICG-HNPCC, suspected HNPCC, and sporadic early onset colorectal cancer

GroupFrequency (%)Probability (P)a
Control group5/50 (10)
ICG-HNPCCb7/35 (20)0.22
Suspected HNPCC8/44 (18)0.37
Early-onset colorectal cancer14/45 (31)0.02
  • a Probability of difference between control group and disease groups.

  • b International Collaborative Group on HNPCC.