Table 2

Effect of treatment with cytotoxic SST analogue AN-238a and cytotoxic radical AN-201a on the percent area of necrosis of U-87MG glioblastomas transplanted into nude mice

Treatment% area of necrosis
Control38 ± 13
AN-238 (day 0)44 ± 7
AN-201 (day 0)31 ± 10
AN-238 (days 0 and 11)63 ± 8
AN-201 (days 0 and 11)34 ± 8
RC-121 (500 μg) s.c. 4 h before AN-23843 ± 4
RC-121 (50 μg/day) s.c. for 7 days before AN-23877 ± 11b
  • a Cytotoxic SST analogue AN-238 and cytotoxic radical AN-201 were injected i.v. at 150 nmol/kg once (day 0) or twice (days 0 and 11).

  • b P = 0.041.