Effect of treatment with cytotoxic SST analogue AN-238a and cytotoxic radical AN-201a on the percent area of necrosis of U-87MG glioblastomas transplanted into nude mice
| Treatment | % area of necrosis |
|---|---|
| Control | 38 ± 13 |
| AN-238 (day 0) | 44 ± 7 |
| AN-201 (day 0) | 31 ± 10 |
| AN-238 (days 0 and 11) | 63 ± 8 |
| AN-201 (days 0 and 11) | 34 ± 8 |
| RC-121 (500 μg) s.c. 4 h before AN-238 | 43 ± 4 |
| RC-121 (50 μg/day) s.c. for 7 days before AN-238 | 77 ± 11b |
a Cytotoxic SST analogue AN-238 and cytotoxic radical AN-201 were injected i.v. at 150 nmol/kg once (day 0) or twice (days 0 and 11).
b P = 0.041.