Table 1

Patient and tumor characteristics, related to the presence or absence of p53 mutations

Portion of mutations in each group
No./all casesPercentageP
Gender0.01
Male68 /11460
Female12 /3435
Age (yrs)
≤59 (males)12 /2450NSa
≤59 (females)4 /757
>60 (males)56 /90620.03
>60 (females)8 /2730
Histological type0.01
SCC44 /6667
AC28 /6844
Large cell carcinoma8 /1457
Differentiation gradeNS
Well15 /3350
Moderate30 /5060
Poor28 /5258
Tumor statusNS
T118 /3256
T250 /9752
T38 /1267
T40 /20
Nodal statusNS
N055 /10552
N19 /2045
N212 /1867
Smokers0.05
Yes71 /12557
Nob1 /617
  • a NS, not significant.

  • b <1 pack-year.