Table 2

Concentration profile of Cats B and L and Stefs A and B by clinical and histopathological prognostic factors and by outcome of disease

VariablenConcentration (ng/mg protein)a
Cat BCat LStef AStef B
Age (yr)
≤ 6024428 (132–1434)11.6 (7.8–40.1)436 (22–2077)328 (37–985)
>6025417 (163–963)4.7 (4.7–26.9)451 (56–1241)283 (73–818)
P NSbNSNSNS
Tumor site
Larynx20425 (241–1434)16.0 (4.7–26.9)510 (56–1764)302 (73–985)
Nonlarynxc29422 (132–957)11.4 (6.7–40.1)420 (22–2077)284 (37–869)
P NSNSNSNS
pT classification
T1+223422 (132–957)10.6 (6.7–40.1)498 (56–2077)371 (73–869)
T3+426425 (185–1434)18.1 (4.7–26.9)416 (22–1764)259 (37–985)
P NS0.005NSNS
pN classification
N024409 (163–1434)13.5 (4.7–26.9)575 (79–1764)375 (96–985)
N1–325423 (132–957)12.3 (6.7–40.1)356 (22–2077)241 (37–818)
P NSNS0.0070.02
TNM stage
SI+II10401 (163–862)9.9 (7.9–26.9)652 (186–1289)455 (248–869)
SIII+IV39422 (132–1434)13.3 (4.7–40.1)407 (22–2077)265 (37–985)
P NS0.050.030.03
Histopathological grade
G1+240415 (132–1434)13.9 (4.7–40.1)455 (22–1764)302 (37–985)
G35462 (163–519)11.1 (8.5–21.0)364 (56–554)265 (73–371)
P NSNSNSNS
Extracapsular spread
Negative9467 (286–957)13.9 (7.8–26.9)308 (56–605)241 (37–625)
Positive16399 (132–713)11.2 (6.7–40.1)385 (22–2077)246 (91–818)
P NSNSNSNS
Outcome of disease
Without RD37413 (132–1434)11.9 (4.7–26.9)488 (22–2077)341 (73–985)
With RD12466 (164–713)15.0 (7.8–40.1)209 (77–536)199 (37–443)
P NSNS0.010.003
  • a Median (range).

  • b NS, not significant; RD, recurrent disease.

  • c Oral cavity, oropharynx, hypopharynx.