Table 3

Prevalence of high-level amplification of various candidate oncogenes in ovarian cancer

Tumor entityAIB1MYBL2PTPN1ZNF217BTAK
Cell lines (n = 8)00252512.5
Sporadic (n = 24)25172912.521
Familial (n = 3)33033330
Hereditarya (n = 4)2505025100
  • For high-level amplification, the copy number is more than three times higher than that of the reference probe. Values are percentages.

  • a Consisting of 2 tumors from BRCA1 and BRCA2 from BRCA2 germline mutation carriers.