Table 2

Radiation sensitivity in combination with nimesulide

Cell lineSF1aSF2aSF0a
NSCLC cell lines
ACC-LC-910.90 ± 0.010.81 ± 0.021.00
ACC-LC-91/NIM 100.79 ± 0.030.72 ± 0.030.85 ± 0.02
ACC-LC-91/NIM 300.72 ± 0.030.69 ± 0.030.80 ± 0.02
ACC-LC-3230.91 ± 0.020.80 ± 0.021.00
ACC-LC-323/NIM 100.85 ± 0.020.74 ± 0.030.91 ± 0.01
ACC-LC-323/NIM 300.68 ± 0.030.63 ± 0.030.84 ± 0.02
ACC-LC-3190.98 ± 0.010.97 ± 0.011.00
ACC-LC-319/NIM 100.90 ± 0.020.90 ± 0.020.92 ± 0.02
ACC-LC-319/NIM 300.88 ± 0.020.87 ± 0.020.90 ± 0.02
ACC-LC-330.87 ± 0.020.83 ± 0.021.00
ACC-LC-33/NIM 100.80 ± 0.030.77 ± 0.030.95 ± 0.01
ACC-LC-33/NIM 300.72 ± 0.030.67 ± 0.030.91 ± 0.02
Normal lung epithelial cell lines
BEAS2B0.90 ± 0.010.82 ± 0.021.00
BEAS2B/NIM 100.91 ± 0.020.84 ± 0.021.01 ± 0.01
BEAS2B/NIM 300.90 ± 0.020.85 ± 0.020.99 ± 0.01
HPL1D0.89 ± 0.010.84 ± 0.021.00
HPL1D/NIM 100.90 ± 0.020.85 ± 0.020.99 ± 0.01
HPL1D/NIM 300.90 ± 0.020.84 ± 0.020.98 ± 0.02
  • a Surviving fractions for 1 Gy, 2 Gy, and 0 Gy.

  • b The values represent means ± SD of a representative experiment. Similar results were obtained in three independent experiments.