Table 1

mIC50 values of GEM and CDDP in human ATC cell lines

Drug (exposure time)IC50m)a
SW1736C6438505CHTh74
GEM (1 h)0.35 ± 0.040.8 ± 0.11.56 ± 0.333.4 ± 2.42
(24 h)0.15 ± 0.0270.16 ± 0.0230.017 ± 0.00280.51 ± 0.11
CDDP (1 h)41.8 ± 10.37 ± 5.4831 ± 9.7612.3 ± 2.52
(24 h)2.23 ± 0.450.28 ± 0.121.3 ± 0.270.8 ± 0.1
  • a IC50 values (μm) represent the mean of three to five independent experiments ± SD.