Table 3

Values of serum CEA levels patients with a decline in CEA

Six patients with elevated serum CEA at the time of study entry had declines in their CEA levels. Patients continued to have monthly CEA levels drawn until radiographic evidence of disease progression. The decline in serum CEA is statistically significant by one-tailed t test (P = 0.0066).

Patient	Baseline	wk 4	wk 8	wk 12	wk 16	wk 20	wk 24	wk 28
8	681	327	289	604	700^a
9	204	147	ND^b	163^a
11	273	162	258	331	398	398^a
12	42	ND	32	29	37	38	39	52^a
14	147	116	169	462	524	934^a
28	86	83	77	81^a

^a Value at the time of radiographic progression and removed from study.
^b ND, not done.