Table 4

Gastrointestinal toxicity

Dose level (mg/m²)	No. of patients	Nausea					Vomiting							Diarrhea							Anorexia
Dose level (mg/m²)	No. of patients			1	2	3	1	2	3	4	1	2	3	4	1	2	3	4
240	3	2	1	0	1	0	0	0	2	0	0	0	1	0	0	0
290
No prior AP RT^a	5	1	3	1	1	1	0	1	1	1	0	0	1	2	0	0
Prior AP RT	7	4	0	1	0	0	0	1	2	3	0	1	3	2	0	0
320
No prior AP RT	8	3	3	2	2	2	1	1	3	2	1	1	3	2	0	0
Prior AP RT	5	2	1	1	2	0	0	1	4	0	0	1	2	0	1	0
340	6	2	2	0	2	2	0	0	3	1	0	1	2	2	0	0

^a RT, radiotherapy.