Table 1

Characterization of 35 surgical specimens of transitional cell carcinoma tissue of the bladder and expression of COX as detected by immunoblot and immunohistochemical analysis

Patient no. and tissueaHistopathological findingsCOX-1COX-2
ImmunoblotImmunohistochemistryImmunoblotImmunohistochemistryb
1N+
1TpT1, G2, pNx+
2N+
2TpT1, G2, pNx++ 40%
3TpT1, G2, pNx+
4TpT1, G3, pN−+
5TpT1, G2, pNx+
6TpT1, G3, pN−+
7TpT1, G1, pNx+
8N+
8TpT1, G3, pN−++ 80%
9TpT1, G2, pN−+
10TpT1, G2, pNx+
11TpT1, G2, pN−+
12TpT1, G2, pNx+
13TpT1, G3, pN−+
14TpT1, G2, pNx++ 20%
15TpT1, G3, pNx+
16N+
16TpT2, G3, pN−+
17TpT2, G2, pN−+
18TpT2, G3, pN−++ 20%
19TpT2, G2, pN−+
20N+
20TpT3, G3, pN−+
21N+
21TpT3, G3, pN−++ 30%
22N+
22TpT3, G3, pNx++ 40%
23TpT3, G3, pN−++ 80%
24TpT3, G3, pN+++ 40%
25N+
25TpT3, G3, pN−++100%
26TpT3, G3, pN−+
27TpT3, G3, pN+++ 20%
28TpT3, G3, pN++
29TpT3, G3, pN++
30TpT3, G2, pN−+
31N+
31TpT3, G3, pN−++ 80%
32TpT3, G3, pN−++ 30%
33N+
33TpT4, G3, pN++
34TpT4, G3, pN−+
35TpT4, G2, pN++
  • a N, normal tissue; T, tumor tissue.

  • b Specimens were regarded as COX negative if <5% of the tumor cells were stained. The percentage of positively stained cells is shown.