Table 1

TIG-3 mRNA hybridization in SCC tumors compared with normal overlying or adjacent skin specimens

Aggressive SCCs
Site/MetastasisTumor no.DifferentiationTIG-3 levels compared with tumor
WellModeratePoorOverlying skinAdjacent skin
?96-36569+Marked patchy increaseNAa
Ear96-34065A24+2-fold increaseNA
Parotid, LN, PN
Upper lip, Cheek96-38303A4+2.66-fold increaseNA
Ear96-54304+2.33-fold increaseNA
?97-4570C13+Marked increaseNA
Nose96-39845A8+1.2-fold increaseNo change
Scalp/skull, multiple tumors96-41288A7+2-fold increase1.5-fold increase
Face, multiple tumors96-51845A11+No changeNA
Infraorbital/PN96-38787A1+2-fold increaseNA
Dermis/parotid, L, V96-35269A21+2.33-fold increaseNA
Parotid/LN97-38951E16+NANA
Non-aggressive squamous cell carcinomas
Elbow96 -05316A1+1.2-fold increase1.4-fold increase
Retroauricular96 -51337A2+No changeNo change
Forehead97 -00664D2+No change1.5-fold increase
Ear96-46239A6+1.25-fold increase1.5-fold increase
Forehead97 -09809A6+2-fold increase2.66-fold increase
Forehead97-20557A3+1.2-fold increase1.6-fold increase
Nose96 -35773A6+1.5-fold increase1.5-fold increase
Forehead97-53342A2+1.5-fold increase2-fold increase
Forehead97 -02450A1+1.5-fold increase1.5-fold increase
  • a NA, not available; LN, lymph node; PN, perineural invasion; L, lymphatics; V, vasculature.