Table 2

Reproducibility within/between ACIS instrument(s) for tumor enumeration (bone marrow specimens from breast cancer patients)

Run no.No. of positive tumor cells
Specimen ASpecimen B
Instrument I
1718
2718
3718
4718
5718
Instrument II
1718
2718
3718
4718
5718
Instrument III
1718
2718
3718
4718
5718
  • Bone marrow mononuclear cell preparations from two breast cancer patients were fixed and immunoenzymatically stained using the BM2 monoclonal antibody and the fast red chromogen. To examine the consistency of tumor cell detection and enumeration, each specimen was evaluated after analysis in five separate runs on each of three different ACIS instruments for a total of 15 independent analyses/specimen.