Table 1

Effect of RGD-containing peptides on the growth of human prostate cancer and normal cells

CellsConcentration (μg/ml)cRGDfVRGDRGDS
Viable cells (×105/ml)% ReductionViable cells (×105/ml)% ReductionViable cells (×105/ml)% Reduction
LNCaP01.40 ± 0.103.05 ± 1.752.65 ± 0.15
100.46 ± 0.0467.22.85 ± 1.756.61.95 ± 0.0526.4
200.23 ± 0.1383.62.60 ± 1.4014.81.40 ± 0.2047.2
PC-306.25 ± 0.555.75 ± 0.255.05 ± 2.45
105.85 ± 0.856.45.65 ± 0.051.84.80 ± 2.304.9
205.50 ± 0.4012.05.25 ± 0.058.74.55 ± 2.359.9
HEL04.85 ± 0.053.55 ± 0.052.85 ± 0.05
104.50 ± 0.107.23.50 ± 0.01.42.80 ± 0.201.8
204.10 ± 0.015.53.30 ± 0.307.02.70 ± 0.105.3