Table 3

Toxicities observed with each adjuvant, by grade

QS-21Montanide ISA-51Total
None123None123None123%
Local skin, especially pain372731010255
Skin, other841018418
Flu-like symptoms102721174122
Headache939118418
Other pain102102029
Stomatitis12912115
Esophageal spasm111102115
Other gastrointestinal101191192114
Hematological111102115
Syncope111102115
Other neurological1119120119
Dyspnea12912115
Endocrine12912115
Urinary12912115
Any09216316123173