Table 5

Treatment of the JMN human mesothelioma with various platinum compoundsa

RxWeight change (%)Average tumor diameter (mm ± SE)bChange in tumor vol (mm3)No. of animals
AgentDose (mg/kg)
+19.1 ± 2+17149
CDDP2−44.2 ± 1+529
CBDCA50−34.3 ± 1+539
OXDCA7−57.8 ± 2+9509
  • a See text for experimental details. Average of three experiments of the 3 mice/group.

  • b Initial tumor diameter was 4.3 ± 1 mm (43 mm3).