Table 4

Response rates at 6 and 12 months with patients classified as responders and nonrespondersa (n = 36)

End pointTreatment group
Placebo4-HPR
6-mo responders75
6-mo nonresponders915
Response rate44%25%
6-mo proportionate difference (95% confidence interval)0.19
(−0.13–0.49)
P = 0.25
12-mo responders82
12-mo nonresponders812
Response rate50%14%
12-mo proportionate difference (95% confidence interval)0.36
(0.2–0.65)
P = 0.04
  • a Not considering crossover.