Table 1

Binding of hTERT and control peptides to human HLA-A3 antigen

NameSequenceProteinPosition (amino acid)ScoreaFluorescence indexb
K973KLFGVLRLKhTERT9731013.5
G804GLFDVFLRFhTERT8042700.0
R535RLREEILAKhTERT535900.0
I265ILRGSVAHK (positive control)Influenza NP265903.9
I540ILAKFLHWL (HLA-A2 peptide)hTERT54000.0
  • a Calculated score in arbitrary units based on http://bimas.dcrt.nih.gov/molbio/hla_bind.

  • b (Mean fluorescence with peptide − mean fluorescence without peptide)/(Mean fluorescence without peptide); results are representative of three experiments.