Table 10

Reported toxicities using the NCI toxicity scalea

Toxicity4-HPR gradePlacebo grade
1212
Alopecia1020
Anisocoria1000
Anorexia0020
Cheilitis3000
Conjunctivitis1000
Diarrhea1011
Dry eyes1000
Dry nasal mucosa1100
Dry skin1010
Fatigue1010
Headache0010
Insomnia0010
Mood1000
Nausea alone1020
Nyctalopia1000
Peeling finger tip1100
Photosensitivity1210
Skin rash3002
Skin reaction1010
Stomatitis0021
Totals204154
  • a There were no instances of grade 3–5 toxicity in either arm.