Table 4

Nonhematological toxicity: summary of nonhematological adverse events during treatment with Genasense and mitoxantrone

Adverse eventNo. of patients with toxicity grade first course (all courses)
1234
Fatigue13 (35)0 (1)00
Nausea7 (21)0 (1)00
Anorexia5 (15)1 (2)00
Elevated creatinine2 (8)2 (2)00
Fever2 (3)1 (1)00
Taste change4 (17)000
Arthralgia/Myalgia4 (8)000
Elevated ALPa2 (2)000
Cardiac dysfunction0 (4)000
Weight loss1 (2)000
Headache1 (1)000
Alopecia1 (1)000
Vomiting01 (1)00
Diarrhea00 (1)00
Dry mouth0 (5)000
  • a ALP, alkaline phosphatase.