Patients’ profiles and responses to DC vaccination
HLA-A24 | MAGE-3 | Sites of tumors | No. of DC vaccinations | Clinical response | Previous treatment | Survivala | |
---|---|---|---|---|---|---|---|
Right inguinal LNb | Radical cystectomy | ||||||
F.Y. | + | + | Para-aorta LN | 6 | Complete responsec | Chemotherapy | 2d |
75 yr F | Right external iliac LN | Radiation | |||||
G.K. 65 yr M | + | + | Iliac LN Para-aorta LN Liver Braine | 18 | Partial response of para-aorta LN and complete response of liver metastasis overall progression | Radical cystectomy Chemotherapy Radiation | 8 |
N.H. 64 yr M | + | + | Bilateral inguinal LN Perineum | 6 | Partial response | TURBT Chemotherapy Radiation | 5 |
N.T. | + | + | Local recurrence | 6 | Progressive disease | Radical cystectomy | 2 |
56 yr M | Pleural dissemination | Chemotherapy | |||||
Radiation |
a Survival is defined as months to death after the DC vaccination.
b LN, lymph node.
c Determined by autopsy.
d Death attributable to perforation of small intestine.
e Solitary brain metastasis developed 6 months after the DC vaccination and was surgically removed.