Table 3

Multivariate analysis of prognostic factors with overall survival

Multivariate analysis was performed using a Cox proportional hazards model.

VariableOSaPHazard ratio (95% CI)
Grade (high)b0.47631.14 (0.79–1.64)
Stage (high)c<0.00011.67 (1.31–2.12)
Nuclear β-cat (neg)d0.87811.02 (0.73–1.31)
Nuclear phospho-β-cat (neg)0.00342.18 (1.30–3.68)
  • a OS, overall survival; CI, confidence interval; β-cat, β-catenin; neg, negative.

  • b High grade was poorly differentiated.

  • c High stage was clinical stage III or IV.

  • d Nuclear β-catenin and phospho-β-catenin negativity was designated as a score of 0 or 1.