Table 1

Clinicopathological characteristics of prostate cancer specimens analyzed and mutation status of PTEN in each case

Case no.Patient Age (yr)Gleason scorePTEN mutation
80NAa7No
82529No
83648No
845110No
85NA10No
86618No
89618Exon 5 (T418C, polymorphism)
90638No
91NA9Exon 2 (A1197G, R55G)
92NA8Exon 5 (T302A, I101A; A403G, I135V)
956010No
96658No
98NA7No
99837No
100759No
101NA9No
102NA7No
103NA9No
104759No
105749No
10783NANo
10871NANo
109NA10Exon 5 (A449G, Q150G)
110659No
111707No
113677Exon 1 (G58T, G20Stop)
114598Exon 8 (C814T, H272Y)
116667No
117NA8Exon 9 (A1086G, polymorphism)
119569No
120NA7No
121667No
42b77Lymph nodeNo
46b75LiverNo
47b70Lymph nodeExon 9 (A1031G, K344R; C1043T, T348I; A1144T, T382S)
48b73Lymph nodeNo
49b75Lymph nodeExon 5 (C328T, Q110Stop)
51b66LiverNo
  • a NA, not available.

  • b Lymph node and liver were the organ sites of metastases.