Table 3

Serum cytokine levels

DoseTNF-α (pg/ml)IL1R-α (pg/ml)
StartEOIaFold increaseStartEOIaFold increase
24 mg/kg331384.245024255.4
341103.276916112.1
14.739.82.7790>3000>3.8
6.7104.615.6409>3000>7.3
30 mg/kg89612.0212356412.7
18573.267959718.8
1473692.5227455522.4
  • a EOI, end of infusion (24 h).