Table 2

Effect of TNP-470 on disease establishment in tail vein model

Mouse (treatment)Disease by locationa
KidneyAdrenalOvaryLiverLungSpleen
1 (saline)+
2 (saline)+++b
3 (saline)
4 (saline)+++
5 (TNP-470)
6 (TNP-470)
7 (TNP-470)
8 (TNP-470)
  • a +, neuroblastoma present; −, no evidence of disease.

  • b Disease present in the lung hilum.