Table 3

Univariate and multivariate analysis of prognostic factors in HCV-positive HCC patients as evaluated by overall and recurrence-free survival

ParameterOverall survivalRecurrence-free survival
UnivariateMultivariateUnivariateMultivariate
Paχ2PaHazard ratioPaχ2PaHazard ratio
Age (<60 vs. ≥60 years)0.00749.4910.00214.1720.008611.7120.00064.939
Liver cirrhosis0.00418.3720.00383.2970.0029.5260.0023.616
Combined iNOS + COX-2 expression0.04174.9120.02672.9580.01877.8020.00524.237
AFP (ng/ml) (<100 vs. ≥100)0.02554.6550.0312.5990.007610.3170.00133.443
Tumor differentiationb0.00310.230.63121.384
  • a Log-rank or generalized Wilcoxon.

  • b Well, moderate vs. others.