Table 2

Correlation between HercepTest and other tests for HER-2 protein expression

TestNo. of cases scored as
0/1+2+3+
HER-2 3+ positive (HercepTest; n = 42)
 Polyclonal antibody (DAKO)04 (9.5%)38 (90.5%)
 NexES1 (2.4%)5 (11.9%)36 (85.7%)
 CB-1110 (23.8%)7 (16.7%)25 (59.5%)
HER-2 2+ positive (HercepTest; n = 39)
 Polyclonal antibody  (DAKO; n = 38)a6 (15.8%)23 (60.5%)9 (23.7%)
 NexES11 (28.2%)27 (69.2%)1 (2.6%)
 CB-1133 (84.6%)4 (10.3%)2 (5.1%)
HER-2 negative (HercepTest; n = 222)
 Polyclonal antibody  (DAKO; n = 220)a199 (90.5%)18 (8.2%)3 (1.3%)
 NexES211 (95%)11 (5%)0
 CB-11221 (99.5%)1 (0.5%)0
  • a Insufficient material was left to investigate three cases with the polyclonal DAKO antibody.