Table 3

Correlation between FISH and IHC

TestNo. of cases scored as
0/1+2+3+
Amplification in FISH (n = 35)
 HercepTest1 (2.9%)034 (97.1%)
 Polyclonal antibody (DAKO)02 (5.7%)33 (94.3%)
 NexES2 (5.7%)2 (5.7%)31 (88.6%)
 CB-117 (20%)6 (17.1%)22 (62.9%)
No amplification in FISH (n = 172)
 HercepTest131 (76.2%)37 (21.5%)4 (2.3%)
 Polyclonal antibody  (DAKO; n = 169)a116 (68.6%)40 (23.7%)13 (7.7%)
 NexES131 (76.2%)38 (22.1%)3 (1.7%)
 CB-11165 (95.9%)4 (2.3%)3 (1.7%)
  • a Insufficient material was left to investigate three cases with the polyclonal DAKO antibody.