Table 1

Apoptosis and proliferation data (medians) for breast cancer patients

MarkersAll patients (n = 791)LN− (n = 331)LN+ (n = 331)Pa
Apoptosisb3.73.44.1NSc
Mitosisd2.31.73.10.0051
A:M ratio1.501.561.60NS
Mitoses/10 HPFs658NS
MIB-1 (%)e17.816.719.50.0066
  • a Represents value of statistical difference between node-negative and node-positive subsets for each variable.

  • b Apoptotic count per 1000.

  • c NS, not significant.

  • d Mitotic count per 1000.

  • e Percentage of cells that are MIB-1-positive.