Table 1

Summary of ILK immunostaining in human prostate tissues

Statistical analyses comparing negative/focal versus uniform staining patterns between groups were performed by Fisher’s exact 2 two-tailed test. Uniform staining for ILK was significantly different in CaP (groups A and B) versus BPH in noncancer patients (group E; P < 0.002) and versus BPH adjacent to CaP (groups C and D; P < 0.001). The incidence of uniform staining was significantly increased in high-grade CaP versus adjacent BPH (group C; P < 0.001) or versus low-grade CaP (group B; P = 0.003). Uniform staining was not significantly different between low-grade CaP and adjacent BPH (group B versus group D; P = 0.226).
Prostate tissue typeUniformFocalNegative
BPH, noncancer patient (group E)2/27 (7%)17/27 (63%)8/27 (30%)
BPH adjacent to low-grade CaP (group D)0/16 (0%)11/16 (69%)5/16 (31%)
BPH adjacent to high-grade CaP (group C)0/18 (0%)7/18 (39%)11/18 (61%)
Low-grade CaP (total; group B)2/15 (13%)8/15 (53%)5/15 (33%)
 M1 and M1+M22/9 (22%)5/9 (56%)2/9 (22%)
 M20/6 (0%)3/6 (50%)3/6 (50%)
High-grade CaP (total; group A)15/24 (63%)8/24 (33%)1/24 (4%)
 M2+M39/16 (56%)6/16 (38%)1/16 (6%)
 M36/8 (75%)2/8 (25%)0/8 (0%)