Table 1

Frequency of LOH in oral biopsy from the patients with a previous oral or UADT malignancya

3p219p21TP53Multiple lossTotal loss
SCC60 (6/10)b91 (11/12)55 (6/11)69 (9/13)100 (13/13)
CIS/Dysplasia13 (1/8)82 (9/11)40 (2/5)18 (2/11)82 (9/11)
Nonneoplastic14 (2/14)50 (11/22)8 (1/12)5 (1/22)59 (13/22)
Total28 (9/32)69 (31/45)32 (9/28)26 (12/46)76 (35/46)
  • a Difference of LOH frequency at different loci among three groups was statistically tested by Fisher’s exact test (two-sided). Significance of P is further described in “Results.”

  • b Percentage of LOH (number of cases with LOH/number of informative cases).