Table 1

Bone marrow labeling and calculated cell cycle times

Labeling index, IL (%)Cell cycle time,atc (h)
Myeloblasts + promyelocytes
 Control55.5 ± 6.39.1 ± 1.0
 SD/01 (normal mice)75.2 ± 3.46.6 ± 0.3
 G-CSFb (normal mice)56.5 ± 2.37.6 ± 0.4
 SD/01 (neutropenic mice)76.8 ± 1.46.5 ± 0.2
Myelocytes
 Control22.7 ± 3.922.0 ± 3.8
 SD/01 (normal mice)51.1 ± 1.79.8 ± 0.3
 G-CSFb (normal mice)29.4 ± 1.516.2 ± 1.1
 SD/01 (neutropenic mice)52.3 ± 0.89.6 ± 0.2
  • a Assumes duration of DNA synthesis, ts, is 5 h.

  • b Data from Lord et al. (4) .