Table 1

Summary of histological subtype and lesion differentiation, lesion average diameter, Ki-67 score, SPF, lesion aveSUV, maxSUV, PV-corr-maxSUV, and aveFLTflux measured for the 11 lesions evaluated

IDaPatientHistologyLesion average diameter (cm)Ki-67b (%)SPF (%)aveSUV (30–60 min)maxSUV (30–60 min)PV-corr-maxSUV (30–60 min)aveFLTflux
1WABenign inflammatory3.92.51.60.910.900.900.82
2PEUD large cell carcinoma1.6901.63.404.026.825.44
3RHPD squamous cell carcinoma2.477049.34.095.866.224.89
4CIUD large cell carcinoma5.59019.45.396.906.906.25
5GLPD squamous cell carcinoma2.072013.32.462.563.051.97
6CLPD squamous cell carcinoma7.666001.912.32 c 2.01
7CLMD adenocarcinoma2.576062.803.773.922.59
8SRMD adenocarcinoma1.73301.63.284.266.412.85
9WMUD large cell carcinoma3.7702.64.295.605.605.16
10CWBenign inflammatory1.972.500.761.421.751.78
11PTUD large cell carcinoma2.580 d 3.534.644.893.88
  • a ID, identification; UD, undifferentiated; PD, poorly differentiated; MD, moderately differentiated.

  • b Ki-67 is defined: (a) in NSCLCs, as the percentage of tumor cells staining positive for MIB-1; (b) in benign lesions, as the percentage of all cells staining positive for MIB-1.

  • c Lesion 11 underwent a percutaneous core biopsy only, and, after immunohistochemical processing for Ki-67, insufficient tissue remained for flow cytometry.

  • d Lesion 6 was a large squamous cell carcinoma with a large area of central necrosis devoid of FLT uptake. For this reason and because the thickness of the tumor could not be measured, no partial volume correction was performed.