Table 4

Multivariate analysis of p73 expression, sex, age, tumor site, Dukes’ stage, growth pattern, and differentiation in relation to survival in patients with colorectal adenocarcinoma

No. of patientsCancer death rate ratio (95% confidence interval)P
p73 expression0.008
 Negative631.0
 Positive1152.136 (1.191–3.831)
Sex0.510
 Male981.0
 Female801.182 (0.719–1.943)
Age (yr)0.028
 <70921.0
 ≥70861.796 (1.057–3.052)
Site0.459
 Left-sided1071.0
 Right-sided711.206 (0.732–1.972)
Dukes’ stage<0.0001
 A171.0
 B621.916 (0.432–8.516)
 C705.457 (1.295–22.98)
 D2926.905 (6.143–117.84)
Growth pattern0.017
 Expanding691.0
 Infiltrating1091.863 (1.1–3.155)
Differentiation0.984
 Well/moderately1251.0
 Poorly531.005 (0.611–1.654)