Table 2

Molecular expression profiles

MarkerResultNormal n (%)Adenoma n (%)Adenocarcinoma n (%)
Ki-67Posa1 (25)1 (16.7)50 (61.0)
Neg3 (75)5 (83.3)32 (39.0)
p53Pos0 (0)1 (16.7)52 (58.4)
Neg4 (100)5 (83.3)37 (41.6)
Mdm-2Pos0 (0)2 (40)b47 (58)
Neg4 (100)3 (60)34 (42)
p27ncPos0 (0)d0 (0)29 (34.1)
Neg1 (100)6 (100)56 (65.9)
p27cPos0 (0)e0 (0)20 (23.3)
Neg2 (100)6 (100)66 (76.7)
Bcl-2Pos2 (50)2 (40)b21 (25.0)
Neg2 (50)3 (60)63 (75)
Cyclin-D1Pos0 (0)0 (0)7 (8.0)
Neg4 (100)6 (100)81 (92.0)
p21Pos0 (0)0 (0)41 (48.2)
Neg2 (100)e6 (100)44 (51.8)
  • a Pos, positive; Neg, negative.

  • b One case lost.

  • c n, nucleas staining; c, cytoplasmic staining.

  • d Three cases lost.

  • e Two cases lost.