Table 4

Outcome according to molecular expression profiles

MarkernLR n (%)DR n (%)5-yr DFS95% CIaLog-rank (P)MVA
p53±524 (7.7)11 (21.2)73%73.7–93.40.69NS
371 (2.7)8 (21.7)76%70.9–93.2
Ki-67±504 (8.0)8 (16.0)78%77.7–96.60.44NS
22 (6.2)8 (25.0)69%63.6–88.7
mdm-2±475 (10.6)6 (12.8)79%79.2–97.70.30NS
341 (2.9)10 (29.4)68%62.7–88.4
Cyclin D1±71 (14.3)1 (14.3)71%42.2–85.80.93NS
805 (6.2)20 (25.0)70%72.3–89.1
Bcl-2±212 (9.5)4 (19.0)71%64.5–96.20.76NS
633 (4.8)13 (20.7)76%76.6–94.4
p21±412976%77.1–96.90.93NS
443972%73.4–90.9
p27±291483%80.6–101.20.06NS
5651664%64.6–85.8
  • a CI, confidence interval; MVA, multivariate analysis; NS, not significant.