Table 5

Urine data following the i.m. injection of crotoxin (0.21 mg/m2)

Time of collection (h)Volume of urine (ml)Crotoxin in urine (ng/ml)Amount excreted in time interval (μg)Excretion rate (μg/h)AUC within interval (ng/min/ml)
0–2100 ± 2068.5 ± 7.57 ± 23.5 ± 161 ± 10
2–4160 ± 3221.2 ± 5.03.5 ± 1.41.75 ± 1.935 ± 7
4–690 ± 2225.1 ± 5.22.8 ± 1.31.4 ± 0.628 ± 9
6–8340 ± 465.9 ± 1.92.1 ± 0.91.05 ± 0.416 ± 4
 8–12192 ± 1818.3 ± 3.13.5 ± 1.00.88 ± 0.523 ± 6
12–24910 ± 433.1 ± 2.02.8 ± 2.40.23 ± 0.220 ± 3