Table 1

In vitro effects of exisulind and docetaxel alone and in combination on cell cycle distribution and % of apoptotic cells in A549 NSCLC cells

Treatment% G1a% S% G2-M% Apoptosis
Control 24 h4638160
Exi 200 μm6022180.1
Exi 300 μm6514210
Doce 0.2 nm4239190
Doce 0.5 nm3841210.05
Doce 1 nm4640140.58
Doce 3 nm32571111
Control 12 h5133160
Docetaxel 6 nm30502034
Docetaxel 10 nm10513964
Control 24 h4638160
Exi 200 μm + Doce 0.2 nm5921200.47
Exi 200 μm + Doce 0.5 nm5428199.4
Exi 200 μm + Doce 1 nm468465
Exi 300 μm + Doce 0.2 nm5817255
Exi 300 μm + Doce 0.5 nm43243339
Exi 300 μm + Doce 1 nm51361362
  • a Exi, exisulind; Doce, docetaxel; % Apoptosis, percentage of apoptotic cells.