Table 2

Relationship between phospho-MAPK/Erk1/2 staining intensity vs. Gleason score

Weak staining had scores of 0 and 1+ and strong staining intensity is 2+ and 3+. The staining intensity for phospho-MAPK/Erk1/2 is significantly greater in normal, hyperplasia, and PIN versus all grades of cancer (P < 0.0001). PIN was significantly greater than normal (P ≤ 0.001) and hyperplasia (P ≤ 0.03).

Gleason scoreNumber of casesWeak staining intensityStrong staining intensity
Normal601743
Hyperplasia532033
PIN51348
2–4936
5–626179
714131
8–1025214