Table 1

Methylation status of bladder tumors

Statistical associations between bladder cancer cases with tumor DNA p14ARF promoter hypermethylation and tumor samples that do not show this alteration in regard to various clinicopathological parameters.

Tumor p14ARF methylTumor p14ARF unmethylP
na%n%
No. of patients1512
Multicentric foci
 Yes151009750.04
 No00325
Tumor size
 ≤3005420.006
 >315100758
Invasion
 Ta–T1960121000.01
 T2–T464000
Stage
 0a–II960121000.01
 III-IV64000
LNE
 Positive42701000.05
 Negative1173120
  • a n, number of cases; LNE, lymph node enlargement.