Table 2

Cytokines modifications after a single infusion of Pamidronate

Median value (pg/dl)95% CI (pg/dl)P (Mann-Whitney U test)
VEGF
 Basal levels745.00654.80–986.26
 1 day602.49424.06–753.250.019
 2 days556.84358.3–640.710.001
 7 days556.88442.49–684.280.03
γ-IFN
 Basal levels12.0011.25–18.65
 1 day21.2818.43–28.650.003
 2 days11.5311.70–18.39n.s.
 7 days9.72510.17–16.48n.s.
IL-6
 Basal levels9.816.8–12.2
 1 day14.1611.8–16.80.007
 2 days11.717.1–12.6n.s.
 7 days11.939.1–13.5n.s.