Table 2

Cases with TP53 mutations in the hot spot codon 175

Patients ID No.SubtypeTP53 Mutation
CodonNucleotide exchangeAmino acid change
31fibrillary 175 CGC → CAC+Arginine → Histidine
42fibrillary 175 CGC → CAC+Arginine → Histidine
109fibrillary 175 CGC → CAC+Arginine → Histidine
236 TAC → TGC+Tyrosine → Cysteine
184fibrillary 175 CGC → CAC−Arginine → Histidine
198fibrillary 175 CGC → CAC−Arginine → Histidine