Table 2

Inhibition of [3H]thymidine uptake by USPC cells grown in the presence of Herceptina

Experiment no.Target cellsHerceptin dose (μg/ml)% inhibition
1USPC-1158% (P < 0.01)
261% (P < 0.01)
562% (P < 0.01)
2USPC-2141% (P < 0.01)
552% (P < 0.01)
3USPC-1130% (P < 0.03)
534% (P < 0.03)
4USPC-2122% (P < 0.05)
226% (P < 0.05)
  • a There were six to eight replicates/group. Rituxan was used as control MAb and gave no inhibition when compared with culture medium alone.