Table 1

Patient characteristics of the low- and high-dose treatment groups

Low-dose groupHigh-dose group
n 3641
Sex
 Male24 (67%)24 (59%)
 Female12 (33%)17 (41%)
Age
 Median (yr)6264
 Range (yr)33–7829–83
 <65 yr2121
 >65 yr1520
Primary site
 Colon2426
 Rectum1011
 Not available24
Performance status
 026 (72%)24 (59%)
 19 (25%)14 (34%)
 21 (3%)3 (7%)
Stage at time of diagnosis
 III14 (39%)17 (42%)
 IV12 (33%)16 (39%)
 Other/Not available10 (28%)8 (20%)
Prior chemotherapy32 (89%)34 (83%)
Recall antigen
 Number positive (mean)2.22.2
 Induration (mean in mm)1314
Serum hCG
 <5 mIU/ml31 (86%)37 (90%)
 >5 mIU/ml5 (14%)4 (10%)