Table 2

Patient Characteristics

CharacteristicStudy cohort%
Median age (yrs)39
Male4860
WBC count >30× 109/liter3746
Platelet count >100× 109/liter6176
Hemoglobin level <10 g/dl5163
LDHa level >600 units/liter7391
Karyotype
 Diploid1923
 Ph positive1923
 T (8;14), t(8;2);t(8;22)34
 6q−, 14q+79
 Insufficient metaphases911
 Hyperdiploid45
 Hypodiploid22.5
Immunophenotype:
 Mature B cell67.5
 T cell911
 T-CALLA33.75
 Precursor B78.75
 CALLA4556
 Null56.25
CR rate7391
DFSb32%
OSb34%
  • a LDH, lactate dehydrogenase.

  • b At 5 years.