Table 2

Demographic data, clinical status, EBV IgA titers, EBV DNA quantity in brushing and plasma samples, and multiple gene methylation status in control cases

CodeSexAge (yrs)StatusIgA VCAIgA EABrush EBV DNA copies/actinPlasma EBV DNA copies/mlMethylation status (biopsy/brush)
RASSF1Ap16DAP-kinase
19F41Normal<5NAa30.0007390U/UU/UU/U
28F32Inc IgA320<500U/UU/UU/U
29M21Normal<5NA00U/UU/UU/U
30M55Normal<5NA0.0007190U/UU/UU/U
31F39FH<5NA00U/UU/UU/U
32F62Inc IgA, papilloma80<50.011142100U/UU/UU/U
35F62Normal<5NA0NANDNDND
36F75Inc IgA20800.00166NAU/UU/UU/U
37F64Normal<5<500NDNDND
38F43Normal<5<500NDNDND
39M49FH, Inc IgA20<50.00535438U/UU/UU/U
41M20FH<5NA00NDNDND
42F60Normal<5NA00NDNDND
43F33Inc IgA80<50.0102110NDNDND
45F39Normal<5NA00NDNDND
46F59Inc IgA20NA00NDNDND
49F49Normal<5NA00NDNDND
50M30Inc IgA40NA00NDNDND
52M31Inc IgA160<50.0036930NDNDND
53F49Normal<5NA00NDNDND
55F34FH<5<50.0068920U/UU/UU/U
56M21FH, Inc IgA20<500NDNDND
60M51Inc IgA320<50.8382480U/UU/UU/U
61M80Inc IgA2050.0147960U/UU/UU/U
66F56Normal<5NA00NDNDND
67M66Inc IgA160100.016788U/UU/UU/U
  • a NA, not available; FH, family history of NPC; Inc IgA, increased EBV IgA titer; M, methylated; U, unmethylated; ND, not done.