Table 2

The distribution of polymorphisms in the IL-4Rα gene in RCC patients and controls

OriginGenotypeOR (95% CI)aPGenotypeOR (95% CI)bP
Ile/IleIle/ValVal/ValArg/ArgArg/GlnGln/Gln
Referencesc49 (15.3)142 (44.2)130 (40.5)6 (2.2)51 (18.4)221 (79.8)
Control (M = 122, F = 83)27 (13.1)94 (45.9)84 (41.0)2 (1.0)42 (20.5)161 (78.5)
RCC (M = 110, F = 33)25 (17.5)76 (53.1)42 (29.4)2.0 (1.38–2.90)0.0265 (3.5)40 (30.0)98 (68.5)1.68 (1.03–2.73)0.036
  • a Ile/Ile + Ile/Val versus Val/Val.

  • b Arg/Arg + Arg/Gln versus Gln/Gln.

  • c Values are taken from previous studies of Japanese populations (13 , 18 , 19 , 24 , 25) .